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Cellosaurus 293-SARS2-S (CVCL_A7YI)

[Text version]
Cell line name 293-SARS2-S
Accession CVCL_A7YI
Resource Identification Initiative To cite this cell line use: 293-SARS2-S (RRID:CVCL_A7YI)
Comments Group: SARS-CoV-2 research cell line.
Characteristics: Stable expression of the SARS-CoV-2 Spike protein. For optimal expression, the C-terminal ER-retention signal has been removed. Has a functional furin cleavage site. Recommended for cell-cell fusion assays with ACE2-expressing cells (InvivoGen).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P0DTC2; Human SARS coronavirus 2 (SARS-CoV-2) spike protein (S).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Web pages https://www.invivogen.com/293-sars2-spike
Cross-references
Encyclopedic resources Wikidata; Q107113197
Entry history
Entry creation20-May-2021
Last entry update10-Sep-2024
Version number6