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Cellosaurus RMS-YM (CVCL_A792)

[Text version]
Cell line name RMS-YM
Synonyms RMSYM
Accession CVCL_A792
Resource Identification Initiative To cite this cell line use: RMS-YM (RRID:CVCL_A792)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Doubling time: ~30 hours (PubMed=1906291).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Urachus; UBERON=UBERON_0002068.
Sequence variations
  • Mutation; HGNC; 20893; BCOR; Simple; p.Arg1163Ter (c.3487C>T); ClinVar=VCV000954289; Zygosity=Homozygous (DepMap=ACH-002048).
Disease Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 2Y
Category Cancer cell line
STR profile Source(s): RCB=RCB1695

Markers:
AmelogeninX,Y
CSF1PO11
D5S81812,14
D7S82010,11
D13S31710,11
D16S53911
TH019
TPOX11
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=1906291; DOI=10.1038/bjc.1991.193; PMCID=PMC1972520
Kubo K., Naoe T., Utsumi K.R., Ishiguro Y., Ueda K., Shiku H., Yamada K.
Cytogenetic and cellular characteristics of a human embryonal rhabdomyosarcoma cell line, RMS-YM.
Br. J. Cancer 63:879-884(1991)

PubMed=19235922; DOI=10.1002/gcc.20655
Missiaglia E., Selfe J., Hamdi M., Williamson D., Schaaf G., Fang C., Koster J., Summersgill B.M., Messahel B., Versteeg R., Pritchard-Jones K., Kool M., Shipley J.M.
Genomic imbalances in rhabdomyosarcoma cell lines affect expression of genes frequently altered in primary tumors: an approach to identify candidate genes involved in tumor development.
Genes Chromosomes Cancer 48:455-467(2009)

PubMed=23828214; DOI=10.3892/or.2013.2588
Yamamoto Y., Fukuda K., Fuchimoto Y., Matsuzaki Y., Saikawa Y., Kitagawa Y., Morikawa Y., Kuroda T.
Cetuximab promotes anticancer drug toxicity in rhabdomyosarcomas with EGFR amplification in vitro.
Oncol. Rep. 30:1081-1086(2013)

PubMed=23882450; DOI=10.3389/fonc.2013.00183; PMCID=PMC3713458
Hinson A.R.P., Jones R., Crose L.E.S., Belyea B.C., Barr F.G., Linardic C.M.
Human rhabdomyosarcoma cell lines for rhabdomyosarcoma research: utility and pitfalls.
Front. Oncol. 3:183.1-183.12(2013)

Cross-references
Cell line collections (Providers) RCB; RCB1695
Cell line databases/resources CLO; CLO_0050151
DepMap; ACH-002048
Biological sample resources BioSample; SAMN03472121
Encyclopedic resources Wikidata; Q54950693
Gene expression databases GEO; GSM219743
Polymorphism and mutation databases Cosmic; 687962
Entry history
Entry creation06-Jun-2012
Last entry update02-May-2024
Version number18