Cellosaurus cell line LHCN-M2 (CVCL

Cellosaurus LHCN-M2 (CVCL_8890)

[Text version]

Cell line name

LHCN-M2

Synonyms

LHCN-Myogenic clone no.2

Accession

CVCL_8890

Resource Identification Initiative

To cite this cell line use: LHCN-M2 (RRID:CVCL_8890)

Comments

Part of: ENCODE project common cell types; tier 2.
Population: Caucasian.
Doubling time: 35-40 hours (Evercyte).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 11730; TERT.
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:88357; Cdk4.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Miscellaneous: STR profile from personal communication of Evercyte.
Derived from site: In situ; Muscle, pectoralis major; UBERON=UBERON_0002381.
Cell type: Myoblast; CL=CL_0000056.

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

41Y

Category

Telomerase immortalized cell line

STR profile

Source(s): Evercyte

Markers:

CSF1PO	10,11
D5S818	11,13
D7S820	9,11
D13S317	11,13
D16S539	12
TH01	8,9
TPOX	8
vWA	15,17

Web pages

http://genome.ucsc.edu/ENCODE/protocols/cell/human/LHCNM2_Wold_protocol.pdf
https://evercyte.com/lhcn-m2/
https://www.proteinatlas.org/learn/cellines

Publications

PubMed=17559502; DOI=10.1111/j.1474-9726.2007.00306.x
Zhu C.-H., Mouly V., Cooper R.N., Mamchaoui K., Bigot A., Shay J.W., Di Santo J.P., Butler-Browne G.S., Wright W.E.
Cellular senescence in human myoblasts is overcome by human telomerase reverse transcriptase and cyclin-dependent kinase 4: consequences in aging muscle and therapeutic strategies for muscular dystrophies.
Aging Cell 6:515-523(2007)

Cross-references

Anatomy/cell type resources

BTO; BTO:0005046

Biological sample resources

ENCODE; ENCBS143YWW
ENCODE; ENCBS167FNB
ENCODE; ENCBS205JRH
ENCODE; ENCBS231AAA
ENCODE; ENCBS232AAA
ENCODE; ENCBS233AAA
ENCODE; ENCBS465BRM
ENCODE; ENCBS538OZY
ENCODE; ENCBS632MTU
ENCODE; ENCBS810TWL
ENCODE; ENCBS836YFM

Encyclopedic resources

Wikidata; Q54902470

Experimental variables resources

EFO; EFO_0005714

Entry history

Entry creation

06-Jun-2012

Last entry update

10-Sep-2024

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