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Cellosaurus KK47 (CVCL_8253)

[Text version]
Cell line name KK47
Synonyms KK-47
Accession CVCL_8253
Resource Identification Initiative To cite this cell line use: KK47 (RRID:CVCL_8253)
Comments Part of: BLA-40 bladder carcinoma cell line panel.
Part of: UBC-40 urothelial bladder cancer cell line index.
Population: Japanese.
Doubling time: 23.5 hours (PubMed=470258); 27 hours (PubMed=1353119).
Omics: CNV analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_8254 (KK47/ADM)CVCL_8255 (KK47/DDP10)CVCL_8256 (KK47/DDP20)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
STR profile Source(s): TKG=TKG 0663

Markers:
AmelogeninX
CSF1PO9,10
D5S81811,12,13
D7S8208,12
D13S31712,13.3
D16S5399,10
TH017
TPOX12
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=604596; DOI=10.5980/jpnjurol1928.68.11_1003
Taya T., Kobayashi T., Tsukahara K., Uchibayashi T., Naito K., Hisazumi H., Kuroda K.
In vitro culture of malignant tumor tissues from the human urinary tract.
Nihon Hinyokika Gakkai Zasshi 68:1003-1010(1977)

PubMed=470258; DOI=10.5980/jpnjurol1928.70.5_485
Hisazumi H., Kanokogi M., Nakajima K., Kobayashi T., Tsukahara K., Naito K., Kuroda K., Matsubara F.
Established cell line of urinary bladder carcinoma (KK-47): growth, heterotransplantation, microscopic structure and chromosome pattern.
Nihon Hinyokika Gakkai Zasshi 70:485-494(1979)

PubMed=6244232
Williams R.D.
Human urologic cancer cell lines.
Invest. Urol. 17:359-363(1980)

PubMed=6620776; DOI=10.5980/jpnjurol1928.74.5_704
Koizumi H.
Chemosensitivity of KK-47 bladder cancer cells and KN-41 renal cancer cells heterotransplanted in nude mice.
Nihon Hinyokika Gakkai Zasshi 74:704-718(1983)

PubMed=3708594
Masters J.R.W., Hepburn P.J., Walker L., Highman W.J., Trejdosiewicz L.K., Povey S., Parkar M., Hill B.T., Riddle P.N., Franks L.M.
Tissue culture model of transitional cell carcinoma: characterization of twenty-two human urothelial cell lines.
Cancer Res. 46:3630-3636(1986)

PubMed=1353119; DOI=10.1016/S0022-5347(17)36624-7
Kimiya K., Naito S., Soejima T., Sakamoto N., Kotoh S., Kumazawa J., Tsuruo T.
Establishment and characterization of doxorubicin-resistant human bladder cancer cell line, KK47/ADM.
J. Urol. 148:441-445(1992)

PubMed=24018021; DOI=10.1016/j.eururo.2013.08.052
Allory Y., Beukers W., Sagrera A., Flandez M., Marques M., Marquez M., van der Keur K.A., Dyrskjot L., Lurkin I., Vermeij M., Carrato A., Lloreta J., Lorente J.A., Carrillo-de-Santa-Pau E., Masius R.G., Kogevinas M., Steyerberg E.W., van Tilborg A.A.G., Abas C., Orntoft T.F., Zuiverloon T.C.M., Malats N., Zwarthoff E.C., Real F.X.
Telomerase reverse transcriptase promoter mutations in bladder cancer: high frequency across stages, detection in urine, and lack of association with outcome.
Eur. Urol. 65:360-366(2014)

PubMed=25997541; DOI=10.1186/s12864-015-1450-3; PMCID=PMC4470036
Earl J., Rico D., Carrillo-de-Santa-Pau E., Rodriguez-Santiago B., Mendez-Pertuz M., Auer H., Gomez G., Grossman H.B., Pisano D.G., Schulz W.A., Perez-Jurado L.A., Carrato A., Theodorescu D., Chanock S.J., Valencia A., Real F.X.
The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.
BMC Genomics 16:403.1-403.16(2015)

PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350
Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

Cross-references
Cell line collections (Providers) TKG; TKG 0663
Cell line databases/resources cancercelllines; CVCL_8253
Anatomy/cell type resources BTO; BTO:0003552
Chemistry resources ChEMBL-Cells; CHEMBL3308615
ChEMBL-Targets; CHEMBL614674
PubChem_Cell_line; CVCL_8253
Encyclopedic resources Wikidata; Q54899980
Experimental variables resources EFO; EFO_0022544
Gene expression databases GEO; GSM136247
GEO; GSM492492
GEO; GSM1374600
GEO; GSM1574547
Polymorphism and mutation databases Cosmic; 925824
Cosmic; 2037949
Progenetix; CVCL_8253
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number27