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Cellosaurus OMM-1 (CVCL_6939)

[Text version]
Cell line name OMM-1
Synonyms OMM1; Omm1
Accession CVCL_6939
Resource Identification Initiative To cite this cell line use: OMM-1 (RRID:CVCL_6939)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: 34 hours (PubMed=24994677).
Derived from site: Metastatic; Hypodermis; UBERON=UBERON_0002072.
Sequence variations
Disease Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 74Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-002017; PubMed=22236444; PubMed=24994677

Markers:
AmelogeninX
CSF1PO10,12
D3S135814,17
D5S81811
D7S82013
D8S117910,16
D13S31711,12 (PubMed=22236444)
12 (DepMap=ACH-002017; PubMed=24994677)
D16S5399
D18S5113,14
D21S1130,30.2
FGA20
Penta D9,12
Penta E5,7
TH017
TPOX8,9
vWA19

Run an STR similarity search on this cell line
Publications

PubMed=8621261; DOI=10.1002/(SICI)1097-0215(19960503)66:3<380::AID-IJC19>3.0.CO;2-F
Luyten G.P.M., Naus N.C., Mooy C.M., Hagemeijer A., Kan-Mitchell J., van Drunen E., Vuzevski V., de Jong P.T.V.M., Luider T.M.
Establishment and characterization of primary and metastatic uveal melanoma cell lines.
Int. J. Cancer 66:380-387(1996)

PubMed=16772116; DOI=10.1016/j.cancergencyto.2005.11.016
White J.S., Becker R.L., McLean I.W., Director-Myska A.E., Nath J.
Molecular cytogenetic evaluation of 10 uveal melanoma cell lines.
Cancer Genet. Cytogenet. 168:11-21(2006)

PubMed=22236444; DOI=10.1111/j.1755-148X.2012.00971.x; PMCID=PMC3288394
Griewank K.G., Yu X.-X., Khalili J.S., Sozen M.M., Stempke-Hale K., Bernatchez C., Wardell S., Bastian B.C., Woodman S.E.
Genetic and molecular characterization of uveal melanoma cell lines.
Pigment Cell Melanoma Res. 25:182-187(2012)

PubMed=23849826; DOI=10.1016/j.ejca.2013.06.011
Amaro A., Mirisola V., Angelini G., Musso A., Tosetti F.I., Esposito A.I., Perri P., Lanza F.B., Nasciuti F., Mosci C., Puzone R., Salvi S., Truini M., Poggi A., Pfeffer U.
Evidence of epidermal growth factor receptor expression in uveal melanoma: inhibition of epidermal growth factor-mediated signalling by gefitinib and cetuximab triggered antibody-dependent cellular cytotoxicity.
Eur. J. Cancer 49:3353-3365(2013)

PubMed=24994677; DOI=10.1016/j.molonc.2014.06.004; PMCID=PMC5528590
Amirouchene-Angelozzi N., Nemati F., Gentien D., Nicolas A., Dumont A., Carita G., Camonis J., Desjardins L., Cassoux N., Piperno-Neumann S., Mariani P., Sastre-Garau X., Decaudin D., Roman-Roman S.
Establishment of novel cell lines recapitulating the genetic landscape of uveal melanoma and preclinical validation of mTOR as a therapeutic target.
Mol. Oncol. 8:1508-1520(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_6939
DepMap; ACH-002017
Encyclopedic resources Wikidata; Q54936368
Polymorphism and mutation databases Cosmic; 848331
Cosmic; 899895
Cosmic; 916147
Cosmic; 1628402
Cosmic; 1669126
Cosmic; 2036704
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number25