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Cellosaurus TUHR10TKB (CVCL_5952)

[Text version]
Cell line name TUHR10TKB
Synonyms TUHR-10TKB; OgTs
Accession CVCL_5952
Resource Identification Initiative To cite this cell line use: TUHR10TKB (RRID:CVCL_5952)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
HLA typing Source: PubMed=9914789
Class I
HLA-AA*24:02

Source: PubMed=26589293
Class I
HLA-AA*02:01,24:02
HLA-BB*40:01,40:01
HLA-CC*03:04,03:04
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0
East Asian, North79.7
East Asian, South19.89
South Asian0.4
European, North0
European, South0
Disease Clear cell renal cell carcinoma (NCIt: C4033)
Clear cell renal carcinoma (ORDO: Orphanet_319276)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
STR profile Source(s): RCB=RCB1275

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S8189,12
D7S82010,11
D13S31714
D16S53913
TH019
TPOX8,11
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=9914789; DOI=10.1111/j.1349-7006.1998.tb00515.x; PMCID=PMC5921718
Liu S.-Q., Kawai K., Shiraiwa H., Hayashi H., Akaza H., Hashizaki K., Shiba R., Saijo K., Ohno T.
High rate of induction of human autologous cytotoxic T lymphocytes against renal carcinoma cells cultured with an interleukin cocktail.
Jpn. J. Cancer Res. 89:1195-1201(1998)

PubMed=17284252; DOI=10.1111/j.1349-7006.2007.00421.x; PMCID=PMC11159908
Shimazui T., Ami Y., Yoshikawa K., Uchida K., Kojima T., Oikawa T., Nakamura K., Honda N., Hinotsu S., Miyazaki J., Kunita N., Akaza H.
Prediction of in vitro response to interferon-alpha in renal cell carcinoma cell lines.
Cancer Sci. 98:529-534(2007)

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=28489074; DOI=10.1038/ncomms15165; PMCID=PMC5436135
Sinha R., Winer A.G., Chevinsky M.S., Jakubowski C., Chen Y.-B., Dong Y.-Y., Tickoo S.K., Reuter V.E., Russo P., Coleman J.A., Sander C., Hsieh J.J.-D., Hakimi A.A.
Analysis of renal cancer cell lines from two major resources enables genomics-guided cell line selection.
Nat. Commun. 8:15165.1-15165.10(2017)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. 3rd, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections (Providers) RCB; RCB1275
Cell line databases/resources CLO; CLO_0050896
cancercelllines; CVCL_5952
Cell_Model_Passport; SIDM01454
DepMap; ACH-000459
Anatomy/cell type resources BTO; BTO:0003732
Biological sample resources BioSample; SAMN03472180
BioSample; SAMN10987736
CRISP screens repositories BioGRID_ORCS_Cell_line; 354
Chemistry resources PharmacoDB; TUHR10TKB_1610_2019
Encyclopedic resources Wikidata; Q54973368
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887715
GEO; GSM888808
Polymorphism and mutation databases IARC_TP53; 30183
LiGeA; CCLE_294
Progenetix; CVCL_5952
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number23