Cellosaurus logo
expasy logo

Cellosaurus SNU-899 (CVCL_5105)

[Text version]
Cell line name SNU-899
Synonyms SNU899; NCI-SNU-899
Accession CVCL_5105
Resource Identification Initiative To cite this cell line use: SNU-899 (RRID:CVCL_5105)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 48 hours (PubMed=10369293).
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
Sequence variations
  • Mutation; HGNC; 5173; HRAS; Simple; p.Gly13Arg (c.37G>C); ClinVar=VCV000035554; Zygosity=Heterozygous (DepMap=ACH-000692).
HLA typing Source: PubMed=26589293
Class I
HLA-AA*02:06,02:06
HLA-BB*15:01,15:01
HLA-CC*04:01,04:01
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.85
East Asian, North62.64
East Asian, South35.88
South Asian0
European, North0
European, South0.63
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A6IV (SNU-899 R1)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): KCLB=00899

Markers:
AmelogeninX
CSF1PO12
D3S135817
D5S81811
D7S82010,13
D13S3178
FGA21
TH019,9.3
TPOX8,11
vWA14,18

Run an STR similarity search on this cell line
Publications

CLPUB00001
Kim K.H., Chung P.-S., Park H.M., Rhee C.-S., Park J.-G.
Establishment and characterization of cell lines derived from squamous cell carcinoma of the head and neck.
Korean J. Head Neck Oncol. 12:181-187(1996)

PubMed=10369293; DOI=10.1097/00005537-199906000-00025
Ku J.-L., Kim W.-H., Lee J.-H., Park H.-S., Kim K.H., Sung M.-W., Park J.-G.
Establishment and characterization of human laryngeal squamous cell carcinoma cell lines.
Laryngoscope 109:976-982(1999)

CLPUB00626
Chon K.-M., Wang S.-G., Lee B.-J., Lee J.-C., Koo H.-J., Kim S.-H.
Establishment of cisplatin resistant head and neck cancer cell lines and cross-resistance of docetaxel.
Korean J. Otolaryngol. 48:651-655(2005)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1; PMCID=PMC2785416
Ku J.-L., Park J.-G.
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=17923759; DOI=10.3346/jkms.2007.22.S.S73; PMCID=PMC2694390
Lee B.-J., Lee B.-H., Wang S.-G., Lee J.-C., Roh H.-J., Goh E.-K., Kim C.-M., Jun E.-S.
Change of the expression of human telomerase reverse transcriptase mRNA and human telomerase RNA after cisplatin and 5-fluorouracil exposure in head and neck squamous cell carcinoma cell lines.
J. Korean Med. Sci. 22 Suppl. 1:S73-S78(2007)

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. 3rd, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections (Providers) KCLB; 00899
Cell line databases/resources cancercelllines; CVCL_5105
Cell_Model_Passport; SIDM00169
DepMap; ACH-000692
Anatomy/cell type resources BTO; BTO:0005925
Biological sample resources BioSample; SAMN10988086
Chemistry resources PharmacoDB; SNU899_1488_2019
Encyclopedic resources Wikidata; Q54955284
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887642
GEO; GSM888734
Polymorphism and mutation databases Cosmic; 934175
IARC_TP53; 30171
LiGeA; CCLE_315
Progenetix; CVCL_5105
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number27