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Cellosaurus SNU-8 (CVCL_5096)

[Text version]
Cell line name SNU-8
Synonyms SNU8
Accession CVCL_5096
Resource Identification Initiative To cite this cell line use: SNU-8 (RRID:CVCL_5096)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 44 hours (PubMed=9299249).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (DepMap=ACH-000460).
  • Mutation; HGNC; 11998; TP53; Simple; p.Pro142fs (c.425_426delCT); Zygosity=Homozygous (DepMap=ACH-000460).
HLA typing Source: PubMed=26589293
Class I
HLA-AA*02:06,24:02
HLA-BB*39:01,40:02
HLA-CC*03:04,03:04
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.06
Native American0.79
East Asian, North58.48
East Asian, South40.21
South Asian0
European, North0.01
European, South0.45
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 55Y
Category Cancer cell line
STR profile Source(s): KCLB=00008

Markers:
AmelogeninX
CSF1PO9,12
D3S135814,16
D5S81811,12
D7S8208,12
D13S3178,9
FGA20,26
TH017,9
TPOX11
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=9299249; DOI=10.1006/gyno.1997.4785
Yuan Y., Kim W.-H., Han H.S., Lee J.-H., Park H.-S., Chung J.-K., Kang S.-B., Park J.-G.
Establishment and characterization of human ovarian carcinoma cell lines.
Gynecol. Oncol. 66:378-387(1997)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1; PMCID=PMC2785416
Ku J.-L., Park J.-G.
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=23839242; DOI=10.1038/ncomms3126; PMCID=PMC3715866
Domcke S., Sinha R., Levine D.A., Sander C., Schultz N.
Evaluating cell lines as tumour models by comparison of genomic profiles.
Nat. Commun. 4:2126.1-2126.10(2013)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. 3rd, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections (Providers) KCLB; 00008
Cell line databases/resources cancercelllines; CVCL_5096
Cell_Model_Passport; SIDM01437
DepMap; ACH-000460
Biological sample resources BioSample; SAMN10988094
CRISP screens repositories BioGRID_ORCS_Cell_line; 696
Chemistry resources PharmacoDB; SNU8_1482_2019
Encyclopedic resources Wikidata; Q54955270
Gene expression databases ArrayExpress; E-MTAB-2770
Polymorphism and mutation databases IARC_TP53; 28385
LiGeA; CCLE_353
Progenetix; CVCL_5096
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number23