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Cellosaurus AG07613 (CVCL_4N94)

[Text version]
Cell line name AG07613
Synonyms AG07613A; AG 7613A; AG07613B
Accession CVCL_4N94
Resource Identification Initiative To cite this cell line use: AG07613 (RRID:CVCL_4N94)
Comments Part of: Canadian Alzheimer disease kindred subcollection.
Population: Caucasian.
Doubling time: Slow growth (Coriell=AG07613).
Karyotypic information: 46,XY,inv(Y)(pter->p11.2::q12->p11.2::q12->qter) (Coriell=AG07613).
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; 9508; PSEN1; Simple; p.Ala246Glu (c.737C>A); ClinVar=VCV000018125; Zygosity=Unspecified (from inference of kindred).
Disease Alzheimer's disease 3 (NCIt: C123412)
Early-onset autosomal dominant Alzheimer disease (ORDO: Orphanet_1020)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_4N95 ! AG07614
Sex of cell Male
Age at sampling 66Y
Category Finite cell line
Publications

CLPUB00597
National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994)

PubMed=8643543; DOI=10.1073/pnas.93.10.5146; PMCID=PMC39422
Parshad R., Sanford K.K., Price F.M., Melnick L.K., Nee L.E., Schapiro M.B., Tarone R.E., Robbins J.H.
Fluorescent light-induced chromatid breaks distinguish Alzheimer disease cells from normal cells in tissue culture.
Proc. Natl. Acad. Sci. U.S.A. 93:5146-5150(1996)

Patent=US5773219
Sanford K.K., Parshad R., Robbins J.H.
Process for detecting Alzheimer disease using cultured cells.
Patent number US5773219, 30-Jun-1998

Cross-references
Cell line collections (Providers) Coriell; AG07613
Cell line databases/resources CLO; CLO_0032828
Encyclopedic resources Wikidata; Q54740874
Entry history
Entry creation22-Sep-2015
Last entry update02-May-2024
Version number12