ID   CHO-6
AC   CVCL_4700
SY   CHO6; CHO 6
DR   BTO; BTO:0003450
DR   Wikidata; Q54812618
RX   PubMed=12379725;
RX   PubMed=16925789;
CC   Characteristics: Resistant to infection by Chlamydia pneumoniae, Chlamydia psittaci and Chlamydia trachomatis.
CC   Characteristics: Has a defect in the processing of the signal sequence of P4HB/PDIA1 which lead to impaired chlamydial attachment and infectivity.
CC   Transformant: ChEBI; CHEBI:23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_0214 ! CHO-K1
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 10
//
RX   PubMed=12379725; DOI=10.1128/IAI.70.11.6444-6447.2002;
RA   Fudyk T., Olinger L., Stephens R.S.;
RT   "Selection of mutant cell lines resistant to infection by Chlamydia
RT   spp.";
RL   Infect. Immun. 70:6444-6447(2002).
//
RX   PubMed=16925789; DOI=10.1111/j.1462-5822.2006.00783.x;
RA   Conant C.G., Stephens R.S.;
RT   "Chlamydia attachment to mammalian cells requires protein disulfide
RT   isomerase.";
RL   Cell. Microbiol. 9:222-232(2007).
//