Cellosaurus PCM6 (CVCL_4666)
Cell line name | PCM6 | ||||||||||||||||||
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Synonyms | PCM-6 | ||||||||||||||||||
Accession | CVCL_4666 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: PCM6 (RRID:CVCL_4666) | ||||||||||||||||||
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Population: Japanese. Characteristics: Produces IgG lambda. Characteristics: IL6 dependent. Doubling time: ~40-50 hours (PubMed=8112425). Omics: Deep exome analysis. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Omics: Transcriptome analysis by RNAseq. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: B-cell; CL=CL_0000236. | ||||||||||||||||||
Sequence variations |
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Genome ancestry | Source: PubMed=30894373
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Disease | Plasma cell myeloma (NCIt: C3242) Multiple myeloma (ORDO: Orphanet_29073) | ||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
Sex of cell | Female | ||||||||||||||||||
Age at sampling | 63Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): RCB=RCB1460 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Web pages | https://www.keatslab.org/myeloma-cell-lines/hmcl-characteristics | ||||||||||||||||||
Publications | PubMed=8112425 DOI=10.1007/0-306-46877-8_4 PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2 DOI=10.1016/B978-0-12-221970-2.50457-5 PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027 CLPUB00604 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103 PubMed=32123307; DOI=10.1038/s41375-020-0785-1; PMCID=PMC7483300 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections (Providers) | RCB; RCB1460 | ||||||||||||||||||
Cell line databases/resources | CLO; CLO_0051009
cancercelllines; CVCL_4666 Cell_Model_Passport; SIDM01776 DepMap; ACH-001162 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03472144
BioSample; SAMN10987723 | ||||||||||||||||||
Chemistry resources | PharmacoDB; PCM6_1255_2019 | ||||||||||||||||||
Encyclopedic resources | Wikidata; Q54938733 | ||||||||||||||||||
Gene expression databases | GEO; GSM887507
GEO; GSM888589 | ||||||||||||||||||
Polymorphism and mutation databases | IARC_TP53; 28305
Progenetix; CVCL_4666 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 10-Sep-2024 | ||||||||||||||||||
Version number | 29 |