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Cellosaurus 4MBr-5 (CVCL_4492)

[Text version]
Cell line name 4MBr-5
Synonyms 4MBR-5
Accession CVCL_4492
Resource Identification Initiative To cite this cell line use: 4MBr-5 (RRID:CVCL_4492)
Comments Group: Non-human primate cell line.
Characteristics: EGF dependent.
Senescence: Senesces at 40 PDL (PubMed=7065527).
Virology: Susceptible to infection by poliovirus type 1, type 2 and type 3 (PubMed=28046048).
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin Macaca mulatta (Rhesus macaque) (NCBI Taxonomy: 9544)
Sex of cell Female
Age at sampling 2-3Y
Category Finite cell line
Publications

CLPUB00288
Caputo J.L., Hay R.J., Williams C.D.
The isolation and properties of an epithelial cell strain from rhesus monkey bronchus.
In Vitro 15:222-223(1979)

PubMed=7065527; DOI=10.1164/arrd.1982.125.2.222
Hay R.J., Williams C.D., Macy M.L., Lavappa K.S.
Cultured cell lines for research on pulmonary physiology available through the American Type Culture Collection.
Am. Rev. Respir. Dis. 125:222-232(1982)

DOI=10.1007/978-94-011-3550-4_4
Hay R.J.
Development, availability and characterization of ATCC human and animal cell lines.
(In book chapter) Animal cell culture and production of biologicals; Sasaki R., Ikura K. (eds.); pp.27-39; Springer; Dordrecht; Netherlands (1991)

DOI=10.1016/B978-012361946-4/50009-0
Hay R.J.
Animal cells in culture.
(In book chapter) Maintaining cultures for biotechnology and industry; Hunter-Cevera J.C., Belt A. (eds.); pp.161-187; Academic Press; San Diego; USA (1996)

PubMed=28046048; DOI=10.1371/journal.pone.0169391; PMCID=PMC5207746
Dotti S., Lombardo T., Villa R., Cacciamali A., Zanotti C., Andreani N.A., Cinotti S., Ferrari M.
Transformation and tumorigenicity testing of simian cell lines and evaluation of poliovirus replication.
PLoS ONE 12:E0169391-E0169391(2017)

Cross-references
Cell line collections (Providers) ATCC; CCL-208
IZSLER; BS CL 222
Cell line databases/resources CLO; CLO_0001400
Encyclopedic resources Wikidata; Q54603515
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number17