• Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (PubMed=29110582; DepMap=ACH-001536).
  

PubMed=12587840
Panichakul T., Wanun T., Reutrakul V., Sirisinha S.
Synergistic cytotoxicity and apoptosis induced in human cholangiocarcinoma cell lines by a combined treatment with tumor necrosis factor-alpha (TNF-alpha) and triptolide.
Asian Pac. J. Allergy Immunol. 20:167-173(2002)

PubMed=15884115; DOI=10.3748/wjg.v11.i18.2748; PMCID=PMC4305909
Tepsiri N., Chaturat L., Sripa B., Namwat W., Wongkham S., Bhudhisawasdi V., Tassaneeyakul W.
Drug sensitivity and drug resistance profiles of human intrahepatic cholangiocarcinoma cell lines.
World J. Gastroenterol. 11:2748-2753(2005)

PubMed=15948244; DOI=10.3748/wjg.v11.i22.3392; PMCID=PMC4315993
Sripa B., Leungwattanawanit S., Nitta T., Wongkham C., Bhudhisawasdi V., Puapairoj A., Sripa C., Miwa M.
Establishment and characterization of an opisthorchiasis-associated cholangiocarcinoma cell line (KKU-100).
World J. Gastroenterol. 11:3392-3397(2005)

PubMed=16475706
Panichakul T., Intachote P., Wongkajornsilp A., Sripa B., Sirisinha S.
Triptolide sensitizes resistant cholangiocarcinoma cells to TRAIL-induced apoptosis.
Anticancer Res. 26:259-265(2006)

PubMed=20493868; DOI=10.1016/j.ijpara.2010.05.002; PMCID=PMC3739719
Yonglitthipagon P., Pairojkul C., Chamgramol Y., Mulvenna J., Sripa B.
Up-regulation of annexin A2 in cholangiocarcinoma caused by Opisthorchis viverrini and its implication as a prognostic marker.
Int. J. Parasitol. 40:1203-1212(2010)

PubMed=21871105; DOI=10.1186/1476-4598-10-102; PMCID=PMC3173387
Obchoei S., Weakley S.M., Wongkham S., Wongkham C., Sawanyawisuth K., Yao Q.-Z., Chen C.-Y.
Cyclophilin A enhances cell proliferation and tumor growth of liver fluke-associated cholangiocarcinoma.
Mol. Cancer 10:102.1-102.15(2011)

CLPUB00275
Zach S., Birgin E., Ruckert F.
Primary cholangiocellular carcinoma cell lines.
J. Stem Cell Res. Transplant. 2:1013-1013(2015)

PubMed=29110582; DOI=10.1177/1010428317725925
Saensa-ard S., Leuangwattanawanit S., Senggunprai L., Namwat N., Kongpetch S., Chamgramol Y., Loilome W., Khansaard W., Jusakul A., Prawan A., Pairojkul C., Khantikeo N., Yongvanit P., Kukongviriyapan V.
Establishment of cholangiocarcinoma cell lines from patients in the endemic area of liver fluke infection in Thailand.
Tumor Biol. 39:1010428317725925-1010428317725925(2017)

PubMed=31077409; DOI=10.1002/hep.30704
Sittithumcharee G., Suppramote O., Vaeteewoottacharn K., Sirisuksakun C., Jamnongsong S., Laphanuwat P., Suntiparpluacha M., Matha A., Chusorn P., Buraphat P., Kakanaporn C., Charngkaew K., Silsirivanit A., Korphaisarn K., Limsrichamrern S., Tripatara P., Pairojkul C., Wongkham S., Sampattavanich S., Okada S., Jirawatnotai S.
Dependency of cholangiocarcinoma on cyclin D-dependent kinase activity.
Hepatology 70:1614-1630(2019)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007; PMCID=PMC9472155
Isidan A., Yenigun A., Soma D., Aksu E., Lopez K., Park Y., Cross-Najafi A., Li P., Kundu D., House M.G., Chakraborty S., Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)