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Cellosaurus J558L (CVCL_3949)

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Cell line name J558L
Synonyms J 558L; J.558 L
Accession CVCL_3949
Resource Identification Initiative To cite this cell line use: J558L (RRID:CVCL_3949)
Comments Group: Hybridoma fusion partner cell line.
Characteristics: Has spontaneously lost the expression of Ig heavy chains (PubMed=6402777).
Cell type: Plasma cell; CL=CL_0000786.
Disease Mouse multiple myeloma (NCIt: C125417)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_3529 (J558)
Children:
CVCL_E8E7 (I3L6)CVCL_B7TP (J558L-CD40L)CVCL_VP27 (J558L-OX40L)
CVCL_M108 (JW183/5/1)CVCL_M109 (JW184/2/1)CVCL_M110 (JW393/A)
CVCL_M111 (JW8/5/13)CVCL_8062 (LT-1 [Mouse])CVCL_J775 (THG1-24)
CVCL_J094 (THG3-B5-13)CVCL_J095 (THG3-MP-2-19-3-8)CVCL_J092 (THM 7.3.5)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Web pages Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/j/cell-lines-detail-45.html
Info; Wikipedia; -; https://en.wikipedia.org/wiki/J558L_cells
Publications

PubMed=6402777; DOI=10.1073/pnas.80.3.825; PMCID=PMC393473
Vernon T. Oi, Sherie L. Morrison, Leonard Arthur Herzenberg, Paul Berg;
Immunoglobulin gene expression in transformed lymphoid cells.
Proc. Natl. Acad. Sci. U.S.A. 80:825-829(1983)

PubMed=6409417; DOI=10.1016/0092-8674(83)90014-4
Stephen D. Gillies, Sherie L. Morrison, Vernon T. Oi, Susumu Tonegawa;
A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene.
Cell 33:717-728(1983)

Cross-references
Cell line collections (Providers) ECACC; 88032902
Cell line databases/resources CLO; CLO_0007002
CLDB; cl2922
Lonza; 14
Anatomy/cell type resources BTO; BTO_0002898
Encyclopedic resources Wikidata; Q6107580
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number19