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Cellosaurus Onda 11 (CVCL_3076)

[Text version]
Cell line name Onda 11
Synonyms Onda-11; no.11; no-11; NO11; Case 3
Accession CVCL_3076
Resource Identification Initiative To cite this cell line use: Onda 11 (RRID:CVCL_3076)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Japanese.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: CRISPR phenotypic screen.
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Brain, right parietal lobe; UBERON=UBERON_0002803.
Sequence variations
  • Mutation; HGNC; 9588; PTEN; Simple; p.Gln17del (c.49_51delCAA); Zygosity=Unspecified (PubMed=10551321).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gly245Ser (c.733G>A); ClinVar=VCV000012365; Zygosity=Unspecified (PubMed=8878451).
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.72
Native American1.06
East Asian, North76.42
East Asian, South17.02
South Asian0
European, North1.56
European, South2.21
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP=908450; DepMap=ACH-001606; JCRB=IFO50369; JCRB=JCRB1605

Markers:
AmelogeninX
CSF1PO9,10,12 (JCRB=JCRB1605)
10,12 (Cosmic-CLP=908450; DepMap=ACH-001606; JCRB=IFO50369)
D3S135817
D5S81810,11
D7S82011 (Cosmic-CLP=908450)
11,12 (DepMap=ACH-001606; JCRB=IFO50369)
11,12,13 (JCRB=JCRB1605)
D8S117910
D13S3178 (Cosmic-CLP=908450; DepMap=ACH-001606; JCRB=IFO50369)
8,9 (JCRB=JCRB1605)
D16S53911
D18S5113,15
D21S1130,31
FGA23
Penta D12,13
Penta E13
TH016,8 (JCRB=JCRB1605)
8 (Cosmic-CLP=908450; DepMap=ACH-001606; JCRB=IFO50369)
TPOX8 (Cosmic-CLP=908450; DepMap=ACH-001606; JCRB=IFO50369)
8,11 (JCRB=JCRB1605)
vWA14,15,17 (JCRB=JCRB1605)
14,17 (Cosmic-CLP=908450; DepMap=ACH-001606; JCRB=IFO50369)

Run an STR similarity search on this cell line
Publications

PubMed=3188836; DOI=10.1007/BF00686381
Onda K., Tanaka R., Washiyama K., Takeda N., Kumanishi T.
Correlation of DNA ploidy and morphological features of human glioma cell cultures with the establishment of cell lines.
Acta Neuropathol. 76:433-440(1988)

CLPUB00089
Onda K., Washiyama K., Tanaka R., Nishiyama A., Usui H., Kumanishi T.
GFAP-positive human glioma cell lines: no.11, no.10.
Hum. Cell 3:251-252(1990)

PubMed=8878451; DOI=10.1111/j.1349-7006.1996.tb02118.x; PMCID=PMC5921198
Zhang S., Endo S., Koga H., Ichikawa T., Feng X., Onda K., Washiyama K., Kumanishi T.
A comparative study of glioma cell lines for p16, p15, p53 and p21 gene alterations.
Jpn. J. Cancer Res. 87:900-907(1996)

PubMed=10551321; DOI=10.1111/j.1349-7006.1999.tb00838.x; PMCID=PMC5926156
Zhang S.-J., Endo S., Ichikawa T., Yoshimura J., Onda K., Tanaka R., Washiyama K., Kumanishi T.
Rare-type mutations of MMAC1 tumor suppressor gene in human glioma cell lines and their tumors of origin.
Jpn. J. Cancer Res. 90:934-941(1999)

PubMed=16232199; DOI=10.1111/j.1349-7006.2005.00099.x; PMCID=PMC11159392
Saigusa K., Hashimoto N., Tsuda H., Yokoi S., Maruno M., Yoshimine T., Aoyagi M., Ohno K., Imoto I., Inazawa J.
Overexpressed Skp2 within 5p amplification detected by array-based comparative genomic hybridization is associated with poor prognosis of glioblastomas.
Cancer Sci. 96:676-683(2005)

PubMed=18415661; DOI=10.1007/s10014-007-0226-0
Tanaka Y., Zhang S.-J., Terasaki H., Koga H., Endo S., Usui H., Washiyama K., Kumanishi T., Uematsu Y., Itakura T.
Frequent and variable abnormalities in p14 tumor suppressor gene in glioma cell lines.
Brain Tumor Pathol. 25:9-17(2008)

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Bignell G.R., Greenman C.D., Davies H.R., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=30971826; DOI=10.1038/s41586-019-1103-9
Behan F.M., Iorio F., Picco G., Goncalves E., Beaver C.M., Migliardi G., Santos R., Rao Y., Sassi F., Pinnelli M., Ansari R., Harper S., Jackson D.A., McRae R., Pooley R., Wilkinson P., van der Meer D.J., Dow D., Buser-Doepner C.A., Bertotti A., Trusolino L., Stronach E.A., Saez-Rodriguez J., Yusa K., Garnett M.J.
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
Nature 568:511-516(2019)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775
Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

Cross-references
Cell line collections (Providers) JCRB; IFO50369
JCRB; JCRB1605
RCB; RCB4500
Cell line databases/resources CLO; CLO_0009899
cancercelllines; CVCL_3076
Cell_Model_Passport; SIDM00573
CGH-DB; 152-1
Cosmic-CLP; 908450
DepMap; ACH-001606
LINCS_LDP; LCL-1387
Biological sample resources BioSample; SAMN03481112
CRISP screens repositories BioGRID_ORCS_Cell_line; 969
Chemistry resources ChEMBL-Cells; CHEMBL3308224
ChEMBL-Targets; CHEMBL2366326
GDSC; 908450
PharmacoDB; no11_1164_2019
PubChem_Cell_line; CVCL_3076
Encyclopedic resources Wikidata; Q54936401
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM1670282
Polymorphism and mutation databases Cosmic; 687580
Cosmic; 908450
Cosmic; 2367542
IARC_TP53; 21592
IARC_TP53; 23806
Proteomic databases PRIDE; PXD030304
Sequence databases EGA; EGAS00001000978
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number38