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Cellosaurus MM415 (CVCL_2608)

[Text version]
Cell line name MM415
Synonyms MM 415
Accession CVCL_2608
Resource Identification Initiative To cite this cell line use: MM415 (RRID:CVCL_2608)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Omics: CNV analysis.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): CBA=CBA-1351; DepMap=ACH-001569

Markers:
AmelogeninX,Y
CSF1PO11
D2S133817,19
D3S135814,15
D5S81811
D7S8209,11
D8S117914
D13S3179,13
D16S53911
D18S5114,20
D19S43314,15.2
D21S1127,28
FGA23,25
Penta D11,13
Penta E10,12
TH016,9
TPOX8,11
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=9354451
Castellano M., Pollock P.M., Walters M.K., Sparrow L.E., Down L.M., Gabrielli B.G., Parsons P.G., Hayward N.K.
CDKN2A/p16 is inactivated in most melanoma cell lines.
Cancer Res. 57:4868-4875(1997)

PubMed=10070891; DOI=10.1038/sj.bjc.6690147; PMCID=PMC2362648
Zerp S.F., van Elsas A., Peltenburg L.T.C., Schrier P.I.
p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis.
Br. J. Cancer 79:921-926(1999)

PubMed=15048078; DOI=10.1038/sj.onc.1207563
Pavey S., Johansson P., Packer L., Taylor J., Stark M.S., Pollock P.M., Walker G.J., Boyle G.M., Harper U., Cozzi S.-J., Hansen K., Yudt L., Schmidt C., Hersey P., Ellem K.A.O., O'Rourke M.G.E., Parsons P.G., Meltzer P.S., Ringner M., Hayward N.K.
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
Oncogene 23:4060-4067(2004)

PubMed=17363583; DOI=10.1158/0008-5472.CAN-06-4152
Stark M.S., Hayward N.K.
Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-density single-nucleotide polymorphism arrays.
Cancer Res. 67:2632-2642(2007)

PubMed=17516929; DOI=10.1111/j.1600-0749.2007.00375.x
Johansson P., Pavey S., Hayward N.K.
Confirmation of a BRAF mutation-associated gene expression signature in melanoma.
Pigment Cell Res. 20:216-221(2007)

Cross-references
Cell line collections (Providers) CBA; CBA-1351
ECACC; 10092319
Cell line databases/resources cancercelllines; CVCL_2608
Cell_Model_Passport; SIDM01907
DepMap; ACH-001569
Biological sample resources BioSample; SAMN07624429
Encyclopedic resources Wikidata; Q54906126
Experimental variables resources EFO; EFO_0022368
Gene expression databases GEO; GSM162933
GEO; GSM226671
Polymorphism and mutation databases Cosmic; 889021
Cosmic; 928751
Cosmic; 2159439
Progenetix; CVCL_2608
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number24