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Cellosaurus COV413A (CVCL_2422)

[Text version]
Cell line name COV413A
Synonyms COV 413A
Accession CVCL_2422
Resource Identification Initiative To cite this cell line use: COV413A (RRID:CVCL_2422)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: OCCP ovarian cancer cell line panel.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Colon, sigmoid; UBERON=UBERON_0001159.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg342Ter (c.1024C>T); ClinVar=VCV000182970; Zygosity=Unspecified (PubMed=25230021; DepMap=ACH-001340).
HLA typing Source: PubMed=26589293
Class I
HLA-AA*02:01,02:01
HLA-BB*07:02,07:02
HLA-CC*07:02,07:02
Disease Ovarian carcinoma (NCIt: C4908)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_2423 ! COV413B
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001340; ECACC=07071905; PubMed=25230021; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10,11
D2S133817
D3S135814
D5S8189,12
D7S8208,13
D8S117913,14
D13S31712
D16S53911
D18S5118
D19S43314,15
D21S1131.2
FGA19
Penta D14
Penta E12,14
TH016
TPOX9
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=8436435; DOI=10.1002/ijc.2910530415
van den Berg-Bakker C.A.M., Hagemeijer A., Franken-Postma E.M., Smit V.T.H.B.M., Kuppen P.J.K., van Ravenswaay Claasen H.H., Cornelisse C.J., Schrier P.I.
Establishment and characterization of 7 ovarian carcinoma cell lines and one granulosa tumor cell line: growth features and cytogenetics.
Int. J. Cancer 53:613-620(1993)

PubMed=9413942; DOI=10.1038/bjc.1997.597; PMCID=PMC2228215
Brouwenstijn N., Slager E.H., Bakker A.B.H., Schreurs M.W.J., van der Spek C.W., Adema G.J., Schrier P.I., Figdor C.G.
Transcription of the gene encoding melanoma-associated antigen gp100 in tissues and cell lines other than those of the melanocytic lineage.
Br. J. Cancer 76:1562-1566(1997)

PubMed=25230021; DOI=10.1371/journal.pone.0103988; PMCID=PMC4167545
Beaufort C.M., Helmijr J.C.A., Piskorz A.M., Hoogstraat M., Ruigrok-Ritstier K., Besselink N., Murtaza M., van IJcken W.F.J., Heine A.A.J., Smid M., Koudijs M.J., Brenton J.D., Berns E.M.J.J., Helleman J.
Ovarian cancer cell line panel (OCCP): clinical importance of in vitro morphological subtypes.
PLoS ONE 9:E103988-E103988(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25877200; DOI=10.1038/nature14397
Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

Cross-references
Cell line collections (Providers) ECACC; 07071905
Cell line databases/resources cancercelllines; CVCL_2422
Cell_Model_Passport; SIDM01478
DepMap; ACH-001340
Biological sample resources BioSample; SAMN03472963
Chemistry resources PharmacoDB; COV413A_255_2019
Encyclopedic resources Wikidata; Q54814344
Experimental variables resources EFO; EFO_0006557
Gene expression databases ArrayExpress; E-MTAB-2706
GEO; GSM1291136
Sequence databases EGA; EGAS00001000610
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number27