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Cellosaurus COR-L321 (CVCL_2414)

[Text version]
Cell line name COR-L321
Synonyms CORL321
Accession CVCL_2414
Resource Identification Initiative To cite this cell line use: COR-L321 (RRID:CVCL_2414)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Caucasian.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis by microarray.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0
East Asian, North0.7
East Asian, South0
South Asian0
European, North67.03
European, South32.26
Disease Lung carcinoma (NCIt: C4878)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP=1322213; DepMap=ACH-001490

Markers:
AmelogeninX
CSF1PO12
D3S135816
D5S81812
D7S82010,11
D8S117910,13
D13S31712,13
D16S53911,12
D18S5114,15
D21S1130
FGA22
Penta D12
Penta E7
TH017,9.3
TPOX8,9
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775
Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

Cross-references
Cell line collections (Providers) ECACC; 96020756
Cell line databases/resources cancercelllines; CVCL_2414
Cell_Model_Passport; SIDM00507
Cosmic-CLP; 1322213
DepMap; ACH-001490
Chemistry resources GDSC; 1322213
PharmacoDB; CORL321_248_2019
Encyclopedic resources Wikidata; Q54814287
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1669702
Proteomic databases PRIDE; PXD030304
Sequence databases EGA; EGAS00001000978
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number23