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Cellosaurus DERL-2 (CVCL_2016)

[Text version]
Cell line name DERL-2
Synonyms DERL2; DERL-NK2
Accession CVCL_2016
Resource Identification Initiative To cite this cell line use: DERL-2 (RRID:CVCL_2016)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: 72 hours (PubMed=11587224); ~60 hours (DSMZ=ACC-531).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Disease Hepatosplenic T-cell lymphoma (NCIt: C8459)
Hepatosplenic T-cell lymphoma (ORDO: Orphanet_86882)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_2017 ! DERL-7
Sex of cell Male
Age at sampling 30Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-531; PubMed=11587224

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133823,24
D3S135814,15
D5S81810,11
D7S82011,12
D8S117913,14
D13S31711,12
D16S53910,11
D18S5114
D19S43313,15
D21S1129,30
FGA20,22 (DSMZ=ACC-531)
21,22 (PubMed=11587224)
Penta D11,13
Penta E11,14
TH019
TPOX8,11
vWA17,19

Run an STR similarity search on this cell line
Publications

PubMed=10800166
Camera A., Pezzullo L., Villa M.R., Luciano L., Pane F., Izzo B., Boccuni P., Di Noto R., Del Vecchio L., Salvatore F., Rotoli B.
Coexistence of two distinct cell populations (CD56(+)TcRgammadelta(+) and CD56(+)TcRgammadelta(-)) in a case of aggressive CD56(+) lymphoma/leukemia.
Haematologica 85:496-501(2000)

PubMed=11587224; DOI=10.1038/sj.leu.2402239
Di Noto R., Pane F., Camera A., Luciano L., Barone M., Lo Pardo C., Boccuni P., Intrieri M., Izzo B., Villa M.R., Macri M., Rotoli B., Sacchetti L., Salvatore F., Del Vecchio L.
Characterization of two novel cell lines, DERL-2 (CD56+/CD3+/Tcry5+) and DERL-7 (CD56+/CD3-/TCRgammadelta-), derived from a single patient with CD56+ non-Hodgkin's lymphoma.
Leukemia 15:1641-1649(2001)

PubMed=28122867; DOI=10.1158/2159-8290.CD-16-0330; PMCID=PMC5402251
McKinney M., Moffitt A.B., Gaulard P., Travert M., de Leval L., Nicolae A., Raffeld M., Jaffe E.S., Pittaluga S., Xi L.-Q., Heavican T., Iqbal J., Belhadj K., Delfau-Larue M.-H., Fataccioli V., Czader M.B., Lossos I.S., Chapman-Fredricks J.R., Richards K.L., Fedoriw Y., Ondrejka S.L., Hsi E.D., Low L., Weisenburger D.D., Chan W.-C., Mehta-Shah N., Horwitz S., Bernal-Mizrachi L., Flowers C.R., Beaven A.W., Parihar M., Baseggio L., Parrens M., Moreau A., Sujobert P., Pilichowska M., Evens A.M., Chadburn A., Au-Yeung R.K.-H., Srivastava G., Choi W.W.-L., Goodlad J.R., Aurer I., Basic-Kinda S., Gascoyne R.D., Davis N.S., Li G.-J., Zhang J., Rajagopalan D., Reddy A., Love C.L., Levy S., Zhuang Y., Datta J., Dunson D.B., Dave S.S.
The genetic basis of hepatosplenic T-cell lymphoma.
Cancer Discov. 7:369-379(2017)

Cross-references
Cell line collections (Providers) DSMZ; ACC-531
Cell line databases/resources CLO; CLO_0037049
cancercelllines; CVCL_2016
Cell_Model_Passport; SIDM01509
DepMap; ACH-001057
DSMZCellDive; ACC-531
LINCS_LDP; LCL-1116
Biological sample resources BioSample; SAMN03473525
Encyclopedic resources Wikidata; Q54830978
Gene expression databases GEO; GSM1374460
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number24