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Cellosaurus UPCI-SCC-029A (CVCL_1855)

[Text version]
Cell line name UPCI-SCC-029A
Synonyms UPCI-SCC-29A; UPCI:SCC029A; UPCISCC029A; UPCI-SCC-029B; UPCI:SCC029B; UPCI:SCC029; SCC029
Accession CVCL_1855
Resource Identification Initiative To cite this cell line use: UPCI-SCC-029A (RRID:CVCL_1855)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Doubling time: ~60 hours (DSMZ=ACC-659).
Derived from site: In situ; Oral cavity, buccal mucosa; UBERON=UBERON_0006956.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg280Thr (c.839G>C); ClinVar=VCV000012368; Zygosity=Heterozygous (PubMed=12872257; DepMap=ACH-001691).
Disease Oral cavity squamous cell carcinoma (NCIt: C4833)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 84Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-659

Markers:
AmelogeninX
CSF1PO11
D2S133817,25
D3S135814,17
D5S81811
D7S8208,9
D8S117912,14
D13S31711,12
D16S53911,12
D18S5114,18.2
D19S43314,15
D21S1129,30
FGA22,23
Penta D13
Penta E10,12
TH016,7
TPOX9,11
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=12872257; DOI=10.1002/humu.10248
Telmer C.A., An J.-Y., Malehorn D.E., Zeng X.-M., Gollin S.M., Ishwad C.S., Jarvik J.W.
Detection and assignment of TP53 mutations in tumor DNA using peptide mass signature genotyping.
Hum. Mutat. 22:158-165(2003)

PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001; PMCID=PMC2025692
White J.S., Weissfeld J.L., Ragin C.C.R., Rossie K.M., Martin C.L., Shuster M., Ishwad C.S., Law J.C., Myers E.N., Johnson J.T., Gollin S.M.
The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines.
Oral Oncol. 43:701-712(2007)

PubMed=17681875; DOI=10.1016/j.oraloncology.2007.05.003; PMCID=PMC2362065
Martin C.L., Reshmi S.C., Ried T., Gottberg W., Wilson J.W., Reddy J.K., Khanna P., Johnson J.T., Myers E.N., Gollin S.M.
Chromosomal imbalances in oral squamous cell carcinoma: examination of 31 cell lines and review of the literature.
Oral Oncol. 44:369-382(2008)

PubMed=24142626; DOI=10.1002/gcc.22115; PMCID=PMC5520977
Parikh R.A., Appleman L.J., Bauman J.E., Sankunny M., Lewis D.W., Vlad A., Gollin S.M.
Upregulation of the ATR-CHEK1 pathway in oral squamous cell carcinomas.
Genes Chromosomes Cancer 53:25-37(2014)

Cross-references
Cell line collections (Providers) DSMZ; ACC-659
Cell line databases/resources cancercelllines; CVCL_1855
DepMap; ACH-001691
DSMZCellDive; ACC-659
Biological sample resources BioSample; SAMN03473472
Encyclopedic resources Wikidata; Q54991569
Polymorphism and mutation databases IARC_TP53; 18351
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number19