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Cellosaurus NY (CVCL_1613)

[Text version]
Cell line name NY
Accession CVCL_1613
Resource Identification Initiative To cite this cell line use: NY (RRID:CVCL_1613)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Japanese.
Doubling time: 21 days (Note=At 18th passage) (PubMed=6596455); ~60 hours (Note=Lot 091198), ~30 hours (Note=Lot 09262016) (JCRB=JCRB0614).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Bone, right femur; UBERON=UBERON_0000981.
HLA typing Source: PubMed=15289353
Class I
HLA-AA*26:01
HLA-BB*55:02
HLA-CC*03:03
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.02
Native American0.2
East Asian, North78.63
East Asian, South19.14
South Asian0.88
European, North0.59
European, South0.55
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP=910849; JCRB=JCRB0614

Markers:
AmelogeninX
CSF1PO12
D5S81813
D7S82011
D13S3178
D16S53910,13
TH017,9
TPOX8
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=6596455
Sekiguchi M., Asanuma K., Satomura T., Fukushima H., Fujii G., Shimoda T., Fukunaga M., Ishikawa E.
A cultured cell line established in vitro from human osteosarcoma.
Jpn. J. Exp. Med. 53:289-292(1983)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=15289353; DOI=10.1158/0008-5472.CAN-04-0522
Tsukahara T., Nabeta Y., Kawaguchi S., Ikeda H., Sato Y., Shimozawa K., Ida K., Asanuma H., Hirohashi Y., Torigoe T., Hiraga H., Nagoya S., Wada T., Yamashita T., Sato N.
Identification of human autologous cytotoxic T-lymphocyte-defined osteosarcoma gene that encodes a transcriptional regulator, papillomavirus binding factor.
Cancer Res. 64:5442-5448(2004)

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Bignell G.R., Greenman C.D., Davies H.R., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775
Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

Cross-references
Cell line collections (Providers) JCRB; JCRB0614
Cell line databases/resources CLO; CLO_0009877
cancercelllines; CVCL_1613
Cell_Model_Passport; SIDM00569
Cosmic-CLP; 910849
DepMap; ACH-002178
LINCS_LDP; LCL-1429
Biological sample resources BioSample; SAMN03471633
Chemistry resources ChEMBL-Cells; CHEMBL3308123
ChEMBL-Targets; CHEMBL1075552
GDSC; 910849
PharmacoDB; NY_1175_2019
PubChem_Cell_line; CVCL_1613
Encyclopedic resources Wikidata; Q54931209
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM320822
GEO; GSM827276
GEO; GSM1670289
Polymorphism and mutation databases Cosmic; 910849
IARC_TP53; 21591
Progenetix; CVCL_1613
Proteomic databases PRIDE; PXD030304
Sequence databases EGA; EGAS00001000978
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number34