Cellosaurus KO52 (CVCL_1321)
Cell line name | KO52 | ||||||||||||||||||
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Synonyms | K052; K-052 | ||||||||||||||||||
Accession | CVCL_1321 | ||||||||||||||||||
Secondary accession | CVCL_8455 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: KO52 (RRID:CVCL_1321) | ||||||||||||||||||
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Population: Japanese. Doubling time: ~48 hours (PubMed=7693050). Microsatellite instability: Instable (MSI-low) (Sanger). Omics: Deep exome analysis. Omics: Deep quantitative proteome analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371. | ||||||||||||||||||
Sequence variations |
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Genome ancestry | Source: PubMed=30894373
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Disease | Adult acute myeloid leukemia (NCIt: C9154) Acute myeloid leukemia (ORDO: Orphanet_519) | ||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
Sex of cell | Male | ||||||||||||||||||
Age at sampling | 46Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): Cosmic-CLP=1330932; JCRB=JCRB0123 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Publications | PubMed=7693050; DOI=10.1182/blood.V82.9.2829.2829 PubMed=10637496; DOI=10.1038/sj.leu.2401604 DOI=10.1016/B978-0-12-221970-2.50457-5 PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662 PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103 PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections (Providers) | JCRB; JCRB0123
JCRB; NIHS0164 - Discontinued | ||||||||||||||||||
Cell line databases/resources | CLO; CLO_0037177
cancercelllines; CVCL_1321 Cell_Model_Passport; SIDM00018 Cosmic-CLP; 1330932 DepMap; ACH-000498 LINCS_LDP; LCL-1080 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03470799
BioSample; SAMN10987820 | ||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308169
ChEMBL-Targets; CHEMBL2366354 GDSC; 907284 PharmacoDB; K052_719_2019 PubChem_Cell_line; CVCL_1321 | ||||||||||||||||||
Encyclopedic resources | Wikidata; Q54900262 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610 GEO; GSM827240 GEO; GSM887233 GEO; GSM888307 GEO; GSM1669969 GEO; GSM1669998 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 749073
Cosmic; 907284 Cosmic; 2131543 Cosmic; 2306214 IARC_TP53; 21425 IARC_TP53; 28223 Progenetix; CVCL_1321 | ||||||||||||||||||
Proteomic databases | PRIDE; PXD030304 | ||||||||||||||||||
Sequence databases | EGA; EGAS00001000978 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 02-May-2024 | ||||||||||||||||||
Version number | 39 |