Cellosaurus AU565 (CVCL_1074)
Cell line name | AU565 | ||||||||||||||||||||||||||||||||||||
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Synonyms | AU-565; AU 565 | ||||||||||||||||||||||||||||||||||||
Accession | CVCL_1074 | ||||||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: AU565 (RRID:CVCL_1074) | ||||||||||||||||||||||||||||||||||||
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Part of: JWGray breast cancer cell line panel. Part of: ICBP43 breast cancer cell line panel. Part of: MD Anderson Cell Lines Project. Part of: MET genetic alteration cell panel (ATCC TCP-1036). Population: Caucasian. Doubling time: 46.31 hours (JWGray panel). Microsatellite instability: Stable (MSS) (Sanger). Omics: Array-based CGH. Omics: CRISPR phenotypic screen. Omics: Deep exome analysis. Omics: Deep quantitative proteome analysis. Omics: DNA methylation analysis. Omics: H2BK120ub ChIP-seq epigenome analysis. Omics: H3K23ac ChIP-seq epigenome analysis. Omics: H3K27ac ChIP-seq epigenome analysis. Omics: H3K27me3 ChIP-seq epigenome analysis. Omics: H3K36me3 ChIP-seq epigenome analysis. Omics: H3K4me1 ChIP-seq epigenome analysis. Omics: H3K4me3 ChIP-seq epigenome analysis. Omics: H3K79me2 ChIP-seq epigenome analysis. Omics: H3K9ac ChIP-seq epigenome analysis. Omics: H3K9me3 ChIP-seq epigenome analysis. Omics: H4K8ac ChIP-seq epigenome analysis. Omics: Protein expression by reverse-phase protein arrays. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Omics: Transcriptome analysis by RNAseq. Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175. | ||||||||||||||||||||||||||||||||||||
Sequence variations |
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HLA typing | Source: PubMed=25960936
Source: PubMed=26589293
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Genome ancestry | Source: PubMed=30894373
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Disease | Breast adenocarcinoma (NCIt: C5214) | ||||||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||||||||||||||||||
Hierarchy | Children:
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Originate from same individual | CVCL_0033 ! SK-BR-3 | ||||||||||||||||||||||||||||||||||||
Sex of cell | Female | ||||||||||||||||||||||||||||||||||||
Age at sampling | 43Y | ||||||||||||||||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||||||||||||||||
STR profile | Source(s): AddexBio=C0006010/4900; ATCC=CRL-2351; Cosmic-CLP=910704; PubMed=25877200 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||||||
Web pages | https://lincs.hms.harvard.edu/resources/reagents/icbp43/ https://www.synapse.org/#!Synapse:syn2346643/wiki/62255 https://tcpaportal.org/mclp/ | ||||||||||||||||||||||||||||||||||||
Publications | PubMed=17157791; DOI=10.1016/j.ccr.2006.10.008; PMCID=PMC2730521 PubMed=18516279; DOI=10.1016/j.molonc.2007.02.004; PMCID=PMC2391005 PubMed=20070913; DOI=10.1186/1471-2407-10-15; PMCID=PMC2836299 PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113 PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027 PubMed=24094812; DOI=10.1016/j.ccr.2013.08.020; PMCID=PMC3931310 PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110; PMCID=PMC3937590 PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981 PubMed=25877200; DOI=10.1038/nature14397 PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469 PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076 PubMed=29273624; DOI=10.1101/gr.226019.117; PMCID=PMC5793780 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 PubMed=30971826; DOI=10.1038/s41586-019-1103-9 PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103 PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254 PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775 | ||||||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||||||
Cell line collections (Providers) | AddexBio; C0006010/4900
ATCC; CRL-2351 | ||||||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0001769
cancercelllines; CVCL_1074 Cell_Model_Passport; SIDM00898 Cosmic-CLP; 910704 DepMap; ACH-000248 LINCS_HMS; 50091 LINCS_LDP; LCL-1462 SLKBase; 3384 | ||||||||||||||||||||||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0004737 | ||||||||||||||||||||||||||||||||||||
Biological sample resources | BioSample; SAMN03470878
BioSample; SAMN03471449 BioSample; SAMN10987882 | ||||||||||||||||||||||||||||||||||||
CRISP screens repositories | BioGRID_ORCS_Cell_line; 333 | ||||||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308095
ChEMBL-Targets; CHEMBL1075393 GDSC; 910704 PharmacoDB; AU565_70_2019 PubChem_Cell_line; CVCL_1074 | ||||||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q54751885 | ||||||||||||||||||||||||||||||||||||
Experimental variables resources | EFO; EFO_0001087 | ||||||||||||||||||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-2770
ArrayExpress; E-MTAB-3610 ArrayExpress; E-TABM-157 ArrayExpress; E-TABM-244 GEO; GSM274658 GEO; GSM344340 GEO; GSM344390 GEO; GSM847196 GEO; GSM847451 GEO; GSM843441 GEO; GSM843442 GEO; GSM886871 GEO; GSM887936 GEO; GSM1053701 GEO; GSM1172939 GEO; GSM1172851 GEO; GSM1238118 GEO; GSM1421428 GEO; GSM1669605 GEO; GSM2258812 GEO; GSM2258813 GEO; GSM2258814 GEO; GSM2258815 GEO; GSM2258816 GEO; GSM2258817 GEO; GSM2258818 GEO; GSM2258819 GEO; GSM2258820 GEO; GSM2258821 GEO; GSM2258822 GEO; GSM2258823 GEO; GSM2258824 GEO; GSM2258825 GEO; GSM2258826 GEO; GSM2258827 GEO; GSM2258828 GEO; GSM2258829 GEO; GSM2258923 GEO; GSM2258924 GEO; GSM2258925 | ||||||||||||||||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 687462
Cosmic; 910704 Cosmic; 1136358 Cosmic; 1176652 Cosmic; 1309002 Cosmic; 1995342 Cosmic; 2165002 IARC_TP53; 21178 LiGeA; CCLE_052 Progenetix; CVCL_1074 | ||||||||||||||||||||||||||||||||||||
Proteomic databases | PRIDE; PXD030304 | ||||||||||||||||||||||||||||||||||||
Sequence databases | EGA; EGAS00001000978 | ||||||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||||||||||||
Last entry update | 02-May-2024 | ||||||||||||||||||||||||||||||||||||
Version number | 39 |