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Cellosaurus Hs 571.T (CVCL_0802)

[Text version]
Cell line name Hs 571.T
Synonyms Hs571T; HS571T
Accession CVCL_0802
Resource Identification Initiative To cite this cell line use: Hs 571.T (RRID:CVCL_0802)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Population: Caucasian.
Omics: Deep exome analysis.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; 2514; CTNNB1; Simple; p.Ser37Ala (c.109T>G); ClinVar=VCV000376235; Zygosity=Homozygous (DepMap=ACH-001092).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (DepMap=ACH-001092).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.08
East Asian, North0.95
East Asian, South0
South Asian1.65
European, North57.56
European, South39.76
Disease Ovarian carcinoma (NCIt: C4908)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ATCC=CRL-7846

Markers:
AmelogeninX
CSF1PO10
D5S81811
D7S8208,9
D13S31710,11
D16S53911,12
TH016,9.3
TPOX8,11
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=23839242; DOI=10.1038/ncomms3126; PMCID=PMC3715866
Domcke S., Sinha R., Levine D.A., Sander C., Schultz N.
Evaluating cell lines as tumour models by comparison of genomic profiles.
Nat. Commun. 4:2126.1-2126.10(2013)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. 3rd, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections (Providers) ATCC; CRL-7846 - Discontinued
Cell line databases/resources CLO; CLO_0004003
cancercelllines; CVCL_0802
Cell_Model_Passport; SIDM01707
DepMap; ACH-001092
Biological sample resources BioSample; SAMN03471106
BioSample; SAMN10988221
Chemistry resources PharmacoDB; Hs571_T_576_2019
Encyclopedic resources Wikidata; Q54895764
Polymorphism and mutation databases IARC_TP53; 28356
Progenetix; CVCL_0802
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number25