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Cellosaurus SG231 (CVCL_0519)

[Text version]
Cell line name SG231
Synonyms PCI:SG231; PCI-SG231; PCI:SG-231
Accession CVCL_0519
Resource Identification Initiative To cite this cell line use: SG231 (RRID:CVCL_0519)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Omics: Deep exome analysis.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Thr125Pro (c.373A>C); ClinVar=VCV000376666; Zygosity=Unspecified (DepMap=ACH-001857).
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 42Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-2126; DepMap=ACH-001857

Markers:
AmelogeninX
CSF1PO10 (ATCC=CRL-2126)
10,11 (DepMap=ACH-001857)
D3S135817
D5S81812
D7S82011
D8S117912,13
D13S3179,10
D16S5399,14 (DepMap=ACH-001857)
14 (ATCC=CRL-2126)
D18S5118
D21S1129
FGA21,21.2
Penta D12,15
Penta E10,13
TH018,9
TPOX8,11
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=2176543; DOI=10.1002/gcc.2870020408
Storto P.D., Saidman S.L., Demetris A.J., Letessier E., Whiteside T.L., Gollin S.M.
Chromosomal breakpoints in cholangiocarcinoma cell lines.
Genes Chromosomes Cancer 2:300-310(1990)

CLPUB00275
Zach S., Birgin E., Ruckert F.
Primary cholangiocellular carcinoma cell lines.
J. Stem Cell Res. Transplant. 2:1013-1013(2015)

PubMed=27231123; DOI=10.1158/2159-8290.CD-15-1442; PMCID=PMC5458737
Saha S.K., Gordan J.D., Kleinstiver B.P., Vu P., Najem M.S., Yeo J.-C., Shi L., Kato Y., Levin R.S., Webber J.T., Damon L.J., Egan R.K., Greninger P., McDermott U., Garnett M.J., Jenkins R.L., Rieger-Christ K.M., Sullivan T.B., Hezel A.F., Liss A.S., Mizukami Y., Goyal L., Ferrone C.R., Zhu A.X.-X., Joung J.K., Shokat K.M., Benes C.H., El-Bardeesy N.
Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity and SRC dependence in intrahepatic cholangiocarcinoma.
Cancer Discov. 6:727-739(2016)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007; PMCID=PMC9472155
Isidan A., Yenigun A., Soma D., Aksu E., Lopez K., Park Y., Cross-Najafi A., Li P., Kundu D., House M.G., Chakraborty S., Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)

Cross-references
Cell line collections (Providers) ATCC; CRL-2126 - Discontinued
Cell line databases/resources MCCL; MCC:0000417
cancercelllines; CVCL_0519
Cell_Model_Passport; SIDM01852
DepMap; ACH-001857
Anatomy/cell type resources BTO; BTO:0002935
Biological sample resources BioSample; SAMN03472551
Encyclopedic resources Wikidata; Q54953156
Experimental variables resources EFO; EFO_0022554
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number24