• Mutation; HGNC; 1092; FOXL2; Simple; p.Cys134Trp (c.402C>G); ClinVar=VCV000376348; Zygosity=Heterozygous (PubMed=19956657; PubMed=20098707).
  

PubMed=11145608; DOI=10.1210/endo.142.1.7862
Nishi Y., Yanase T., Mu Y.-M., Oba K., Ichino I., Saito M., Nomura M., Mukasa C., Okabe T., Goto K., Takayanagi R., Kashimura Y., Haji M., Nawata H.
Establishment and characterization of a steroidogenic human granulosa-like tumor cell line, KGN, that expresses functional follicle-stimulating hormone receptor.
Endocrinology 142:437-445(2001)

PubMed=15541573; DOI=10.1016/j.mce.2004.04.018
Havelock J.C., Rainey W.E., Carr B.R.
Ovarian granulosa cell lines.
Mol. Cell. Endocrinol. 228:67-78(2004)

PubMed=18980698; DOI=10.1186/1471-2407-8-319; PMCID=PMC2584659
Imai M., Muraki M., Takamatsu K., Saito H., Seiki M., Takahashi Y.
Spontaneous transformation of human granulosa cell tumours into an aggressive phenotype: a metastasis model cell line.
BMC Cancer 8:319.1-319.10(2008)

PubMed=19956657; DOI=10.1371/journal.pone.0007988; PMCID=PMC2777318
Schrader K.A., Gorbatcheva B., Senz J., Heravi-Moussavi A., Melnyk N., Salamanca C.M., Maines-Bandiera S.L., Cooke S.L., Leung P.C.K., Brenton J.D., Gilks C.B., Monahan J.E., Huntsman D.G.
The specificity of the FOXL2 c.402C>G somatic mutation: a survey of solid tumors.
PLoS ONE 4:E7988-E7988(2009)

PubMed=20098707; DOI=10.1371/journal.pone.0008789; PMCID=PMC2808356
Benayoun B.A., Caburet S., Dipietromaria A., Georges A., D'Haene B., Pandaranayaka P.J.E., L'Hote D., Todeschini A.-L., Krishnaswamy S., Fellous M., De Baere E., Veitia R.A.
Functional exploration of the adult ovarian granulosa cell tumor-associated somatic FOXL2 mutation p.Cys134Trp (c.402C>G).
PLoS ONE 5:E8789-E8789(2010)

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Bignell G.R., Greenman C.D., Davies H.R., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
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PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
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An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775
Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)