Cellosaurus MV4-11 (CVCL_0064)
Cell line name | MV4-11 | ||||||||||||||||||||||||||||||||||||
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Synonyms | MV-4-11; MV-4:11; MV4:11; MV 4;11; MV4;11; MV411; MV(4;11); MV4II | ||||||||||||||||||||||||||||||||||||
Accession | CVCL_0064 | ||||||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: MV4-11 (RRID:CVCL_0064) | ||||||||||||||||||||||||||||||||||||
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-9591. Population: Caucasian. Characteristics: CSF2 and IL3 dependent. Doubling time: 32 hours (PubMed=25984343); ~48 hours (CLS=300295); ~50 hours (DSMZ=ACC-102). Karyotypic information: 48,XY,t(4;11)(q21;q23),+8,+19 (ATCC=CRL-9591). Microsatellite instability: Stable (MSS) (Sanger). Omics: Acetylation analysis by proteomics. Omics: Deep exome analysis. Omics: Deep quantitative phosphoproteome analysis. Omics: DNA methylation analysis. Omics: shRNA library screening. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Omics: Transcriptome analysis by RNAseq. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. | ||||||||||||||||||||||||||||||||||||
Sequence variations | |||||||||||||||||||||||||||||||||||||
HLA typing | Source: PubMed=26589293
Source: CLS=300295
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Genome ancestry | Source: PubMed=30894373
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Disease | Childhood acute monocytic leukemia (NCIt: C9163) Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514) | ||||||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||||||||||||||||||
Hierarchy | Children:
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Sex of cell | Male | ||||||||||||||||||||||||||||||||||||
Age at sampling | 10Y | ||||||||||||||||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||||||||||||||||
STR profile | Source(s): AddexBio=C0003025/4955; ATCC=CRL-9591; CLS=300295; COG; Cosmic-CLP=908156; DSMZ=ACC-102; PubMed=20922763; PubMed=25877200 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||||||
Web pages | https://web.archive.org/web/20201109215324/www.infarktforschung.de/macrophages_cell_lines.html | ||||||||||||||||||||||||||||||||||||
Publications | PubMed=3496132; DOI=10.1182/blood.V70.1.192.192 PubMed=2656885; DOI=10.1002/stem.5530070202 PubMed=1423625; DOI=10.1016/0092-8674(92)90603-A PubMed=8353274; DOI=10.1182/blood.V82.4.1080.1080 PubMed=8358709 PubMed=9195772; DOI=10.1016/s0925-5710(96)00563-4 DOI=10.1016/B978-0-12-221970-2.50457-5 PubMed=12529668; DOI=10.1038/sj.leu.2402740 PubMed=14504097; DOI=10.1182/blood-2003-02-0418 PubMed=14671638; DOI=10.1038/sj.leu.2403236 PubMed=15843827; DOI=10.1038/sj.leu.2403749 PubMed=16408098; DOI=10.1038/sj.leu.2404081 PubMed=19608861; DOI=10.1126/science.1175371 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662 PubMed=20922763; DOI=10.1002/pbc.22801; PMCID=PMC3005554 PubMed=21552520; DOI=10.1371/journal.pone.0019169; PMCID=PMC3084268 PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027 PubMed=25984343; DOI=10.1038/sdata.2014.35; PMCID=PMC4432652 PubMed=25485619; DOI=10.1038/nbt.3080 PubMed=25877200; DOI=10.1038/nature14397 PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469 PubMed=30285677; DOI=10.1186/s12885-018-4840-5; PMCID=PMC6167786 PubMed=30629668; DOI=10.1371/journal.pone.0210404; PMCID=PMC6328144 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103 PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775 | ||||||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||||||
Cell line collections (Providers) | AddexBio; C0003025/4955
ATCC; CRL-9591 ATCC; HTB-189 - Discontinued CLS; 300295 DSMZ; ACC-102 Ubigene; YC-C060 | ||||||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0007906
CLDB; cl3610 CLDB; cl3611 cancercelllines; CVCL_0064 CCRID; 3101HUMSCSP5031 Cell_Model_Passport; SIDM00657 Cosmic-CLP; 908156 DepMap; ACH-000045 DSMZCellDive; ACC-102 IGRhCellID; MV4II LINCS_LDP; LCL-1092 Lonza; 996 TOKU-E; 2536 | ||||||||||||||||||||||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0006413 | ||||||||||||||||||||||||||||||||||||
Biological sample resources | BioSample; SAMN01821582
BioSample; SAMN01821649 BioSample; SAMN03473104 BioSample; SAMN10988366 | ||||||||||||||||||||||||||||||||||||
CRISP screens repositories | BioGRID_ORCS_Cell_line; 138 | ||||||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308063
ChEMBL-Targets; CHEMBL613835 GDSC; 908156 PharmacoDB; MV411_972_2019 PubChem_Cell_line; CVCL_0064 | ||||||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q54907109 | ||||||||||||||||||||||||||||||||||||
Experimental variables resources | EFO; EFO_0002242 | ||||||||||||||||||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-2706 ArrayExpress; E-MTAB-2770 ArrayExpress; E-MTAB-3610 GEO; GSM236796 GEO; GSM236832 GEO; GSM482560 GEO; GSM887344 GEO; GSM888420 GEO; GSM1374694 GEO; GSM1446746 GEO; GSM1670137 | ||||||||||||||||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 787416
Cosmic; 798673 Cosmic; 908156 Cosmic; 975284 Cosmic; 994182 Cosmic; 996315 Cosmic; 1012104 Cosmic; 1037736 Cosmic; 1078732 Cosmic; 1089516 Cosmic; 1127256 Cosmic; 1150899 Cosmic; 1152712 Cosmic; 1181603 Cosmic; 1278781 Cosmic; 1281340 Cosmic; 1308221 Cosmic; 1319550 Cosmic; 1451846 Cosmic; 1476424 Cosmic; 1516631 Cosmic; 1524837 Cosmic; 1623635 Cosmic; 1696137 Cosmic; 1779133 Cosmic; 2131568 Cosmic; 2306226 Cosmic; 2392908 Cosmic; 2393011 Cosmic; 2542841 Cosmic; 2750867 IARC_TP53; 21521 LiGeA; CCLE_055 Progenetix; CVCL_0064 | ||||||||||||||||||||||||||||||||||||
Proteomic databases | PRIDE; PXD030304 | ||||||||||||||||||||||||||||||||||||
Sequence databases | EGA; EGAS00001000610
EGA; EGAS00001000978 EGA; EGAS00001002554 | ||||||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||||||||||||
Last entry update | 02-May-2024 | ||||||||||||||||||||||||||||||||||||
Version number | 46 |