Cellosaurus AN3-CA (CVCL_0028)
Cell line name | AN3-CA | ||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Synonyms | AN3_CA; AN3 CA; AN3 Ca; AN3CA; AN-3; AN3; Acanthosis Nigricans 3rd attempt-CArcinoma | ||||||||||||||||||||||||||||||||||||
Accession | CVCL_0028 | ||||||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: AN3-CA (RRID:CVCL_0028) | ||||||||||||||||||||||||||||||||||||
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Part of: ERK genetic alteration cell panel (ATCC TCP-1033). Part of: MD Anderson Cell Lines Project. Part of: PTEN genetic alteration cell panel (ATCC TCP-1030). Population: Caucasian. Doubling time: ~45-50 hours (CLS=300119); ~55 hours (DSMZ=ACC-267). Microsatellite instability: Instable (MSI-high) (PubMed=31068700; Sanger). Omics: Array-based CGH. Omics: Chromatin accessibility by ATAC-seq. Omics: Deep antibody staining analysis. Omics: Deep exome analysis. Omics: Deep quantitative proteome analysis. Omics: DNA methylation analysis. Omics: Protein expression by reverse-phase protein arrays. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Omics: Transcriptome analysis by RNAseq. Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029. | ||||||||||||||||||||||||||||||||||||
Sequence variations |
| ||||||||||||||||||||||||||||||||||||
HLA typing | Source: PubMed=26589293
| ||||||||||||||||||||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
| ||||||||||||||||||||||||||||||||||||
Disease | Acanthosis nigricans (NCIt: C26687) Endometrial adenocarcinoma (NCIt: C7359) | ||||||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||||||||||||||||||
Sex of cell | Female | ||||||||||||||||||||||||||||||||||||
Age at sampling | 55Y | ||||||||||||||||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||||||||||||||||
STR profile | Source(s): ATCC=HTB-111; CLS=300119; Cosmic-CLP=910781; DSMZ=ACC-267; IZSLER=BS TCL 200; PubMed=25877200 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||||||
Web pages | https://www.proteinatlas.org/learn/cellines https://tcpaportal.org/mclp/ | ||||||||||||||||||||||||||||||||||||
Publications | PubMed=14207855; DOI=10.1093/jnci/33.3.441 PubMed=327080; DOI=10.1093/jnci/59.1.221 PubMed=6220172 PubMed=3518877; DOI=10.3109/07357908609038260 PubMed=11668190; DOI=10.1177/002215540104901105 PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662 PubMed=20218740; DOI=10.1177/153303461000900207; PMCID=PMC5120669 PubMed=20944090; DOI=10.1126/scitranslmed.3001538 PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027 PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017; PMCID=PMC3432677 PubMed=25485619; DOI=10.1038/nbt.3080 PubMed=25877200; DOI=10.1038/nature14397 PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469 PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103 PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775 | ||||||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||||||
Cell line collections (Providers) | ATCC; HTB-111
BCRJ; 0363 CCTCC; GDC0127 CLS; 300119 DSMZ; ACC-267 IZSLER; BS TCL 200 | ||||||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0001722
CLO; CLO_0037160 cancercelllines; CVCL_0028 CCRID; 4201HUM-CCTCC00127 Cell_Model_Passport; SIDM00901 Cosmic-CLP; 910781 DepMap; ACH-000940 DSMZCellDive; ACC-267 IGRhCellID; AN3CA LINCS_LDP; LCL-1499 TOKU-E; 543 | ||||||||||||||||||||||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0001771 | ||||||||||||||||||||||||||||||||||||
Biological sample resources | BioSample; SAMN03471092
BioSample; SAMN03473131 BioSample; SAMN03473336 BioSample; SAMN10988375 | ||||||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308708
ChEMBL-Targets; CHEMBL1075392 GDSC; 910781 PharmacoDB; AN3CA_63_2019 PubChem_Cell_line; CVCL_0028 | ||||||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q54749896 | ||||||||||||||||||||||||||||||||||||
Experimental variables resources | EFO; EFO_0002110 | ||||||||||||||||||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-783 ArrayExpress; E-MTAB-2706 ArrayExpress; E-MTAB-2770 ArrayExpress; E-MTAB-3610 GEO; GSM374970 GEO; GSM375429 GEO; GSM827494 GEO; GSM886869 GEO; GSM887934 GEO; GSM1669600 GEO; GSM3161710 GEO; GSM3161711 | ||||||||||||||||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 687550
Cosmic; 699283 Cosmic; 713473 Cosmic; 713495 Cosmic; 809134 Cosmic; 846176 Cosmic; 871551 Cosmic; 889116 Cosmic; 910781 Cosmic; 980634 Cosmic; 1007162 Cosmic; 1057760 Cosmic; 1066221 Cosmic; 1070810 Cosmic; 1102376 Cosmic; 1105620 Cosmic; 1177683 Cosmic; 1223484 Cosmic; 1434192 Cosmic; 1576450 Cosmic; 1622894 Cosmic; 1696752 Cosmic; 2030460 Cosmic; 2646618 IARC_TP53; 21175 LiGeA; CCLE_574 Progenetix; CVCL_0028 | ||||||||||||||||||||||||||||||||||||
Proteomic databases | PRIDE; PXD030304 | ||||||||||||||||||||||||||||||||||||
Sequence databases | EGA; EGAS00001000610
EGA; EGAS00001000978 | ||||||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||||||||||||
Last entry update | 10-Sep-2024 | ||||||||||||||||||||||||||||||||||||
Version number | 43 |